Manager, Information Technology

Information Technology · Monrovia, California
Department Information Technology
Employment Type Full Time
Minimum Experience Manager/Supervisor

Xencor is an innovative, clinical-stage biopharmaceutical company located in the Los Angeles area—near Pasadena—and in San Diego. We use our pioneering XmAb® technology to discover and develop better biotherapeutics, antibodies and cytokines with improved function, with the goal of improving patient outcomes and quality of life. We have an excellent opportunity for a Manager, Information Technology to join our team.


Our protein engineering capabilities and the modular nature of our XmAb technology allow us to quickly identify and create new platforms and drug candidates for potential development. We are advancing a deep clinical pipeline of novel drug candidates, including eight bispecific antibodies and two engineered cytokines, and more programs are expected to start clinical testing in 2022. We also leverage our many XmAb technologies by collaborating with leading global biopharmaceutical companies, including Genentech and Janssen Biotech, among others, and including our partnerships, 20 XmAb drug candidates are advancing through clinical development. Three XmAb medicines, to treat patients with a range of serious illnesses, such as aggressive lymphoma, rare blood disorders and COVID-19, are now marketed worldwide by partners.


Our employees are the most important factor in our success, and we have assembled a highly talented group from diverse backgrounds and disciplines to execute our business plan and shape our future. Xencor employees’ value new ideas and flexibility and demand from each other scientific rigor, a passion for innovation, and a willingness to take risks.


This position will be onsite in our Monrovia, CA. office and will move to Pasadena CA. in early 2023


Responsible for managing IT critical infrastructure, lab environment, security, and support functions for the company.

Job Duties Include:

  • Evaluates and anticipates technology for assigned internal client groups
  • Manages IT support to assigned end users
  • Manages training and support for software and hardware requests and problems
  • Oversees the provisioning and deprovisioning of end-user accounts, access, software and hardware
  • Secures, maintains and supports both business and laboratory environments
  • Creates, updates, and reviews departmental procedures, support tickets, and knowledge bases
  • Manages backups and redundancy of all critical IT and laboratory systems
  • Manages ongoing security initiatives including training, education, system hardening, vulnerability scanning and remediation
  • Manages third-party vendor relations and vendor risk management
  • Manages the planning and implementation of IT projects
  • Communicates and presents information to upper management and company-wide
  • Adheres to all department and company-wide policies regarding conduct, performance and procedures
  • Provides oversight and direction to direct and indirect reports, as applicable, in accordance with the organization’s policies and procedures.  The responsibilities may include, but are not limited to recruiting, training, communicating job expectations, appraising and managing job performance, delivering feedback and coaching, and providing career development planning and opportunities
  • Performs other duties as assigned.



Position requires a bachelor’s degree and a minimum of 6 years of related experience. Previous experience performing IT duties in a Windows-based environment and creating and implementing IT security policies also required. Experience working in publicly held company within the biotechnology, pharmaceutical or life sciences industry preferred. Experience applying Governance, Risk, Compliance, and/or Cybersecurity concepts preferred.

Position also requires:

  • Ability to work in a fast-paced environment, while remaining flexible and adaptable
  • Exceptional functional knowledge and experience with Microsoft Office applications, particularly Office 365, and experience with other critical business application
  • Exceptional functional knowledge and experience with system administration in a Microsoft environment covering hardware, software, updates, mail, storage and backups
  • Exceptional functional knowledge and experience with network administration covering IP networking, firewalls, routers, switches, network and security appliances
  • Ability to work on-call and after hours to address urgent IT matters
  • Exceptional functional knowledge and experience with endpoint administration covering desktops, laptops, phones, printers/scanners, and conferencing equipment
  • Exceptional teamwork and collaboration skills working with the IT team, internal business units, partners, third-party vendors and regulators
  • Strong written and verbal communication skills, including the ability to communicate effectively at all levels of the organization
  • Exceptional understanding of the correlation between business and IT
  • Exceptional customer service and documentation skills.

Physical, Mental and Environment Demands:

The physical, mental and working environment demands described are representative of those that must be met by an employee to successfully perform the primary functions of this position.


The working environment for this role may include work in a research laboratory which may involve exposure to hazardous and biohazardous materials including chemical hazards, infectious agents, bloodborne pathogens and animal allergens. The use of personal protective equipment (PPE) for handling hazardous and biohazardous materials may be required.  See additional requirements for jobs requiring work in the laboratory listed below.


The physical demands of the office are normally associated with extended amounts of time sitting and using office equipment, including a computer, keyboard and mouse, which can cause muscle strain. While performing the duties of this job, the employee is frequently required to stand, walk and sit. Periodic light lifting of supplies and materials may apply.


Specific mental demands for the position are listed above under requirements.  In addition, mental demands for this position include:

  • Ability to multitask without loss of efficiency or accuracy, including the ability to perform multiple duties from multiple sources.
  • Ability to work and sustain attention with distractions and/or interruptions.
  • Ability to interact appropriately with a variety of individuals including vendors, customers and clients.
  • Ability to maintain regular attendance and be punctual.
  • Ability to understand, remember and follow verbal and written instructions.

Additional Requirements for Laboratory and Research Related Jobs

This role may involve exposure to experimental subjects and/or specimens including infected samples, plus various Hazardous Materials and infectious agents (Bloodborne Pathogens, or other potentially infections materials (OPIMs). Therefore, the following are also required:

  • Ability to follow the established Environmental Health & Safety rules, procedures, and/or BioSafety Guidelines
  • Ability to read and understand Safety Data Sheets (SDSs)
  • Knowledge of biosafety techniques and aseptic/gowning practices
  • Experience with laboratory safety standards and procedures, including biohazard handling and disposal techniques, and the ability to ensure laboratory compliance with required safety regulations

Occasional travel may be required, including travel between Xencor’s Monrovia and San Diego offices. Work for this position is generally performed at Xencor’s worksite and requires full-time commitment.


Xencor requires all employees to be fully vaccinated against COVID-19 as a condition of employment.  Being fully vaccinated means that at least two weeks have passed since an individual’s final dose of an authorized COVID-19 vaccine regimen, including any boosters recommended by the CDC.  New employees will be required to provide proof of their fully COVID-19 vaccinated status as of their start date unless an exemption or accommodation is approved. 

Americans with Disabilities Act (ADA) Statement

The Company will provide reasonable accommodations (such as a qualified sign language interpreter or other personal assistance) with the application process upon your request as required to comply with applicable laws. If you have a disability and require assistance in this application process, please contact


To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. Reasonable Accommodations may be made to enable qualified individuals with disabilities to perform the essential functions.


Equal Employment Opportunity (EEO) Statement

The Company is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender or gender identity, national origin, disability status, protected veteran status or any other characteristic protected by state or federal law.


Xencor does not accept profiles or resumes from recruiting vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by Xencor, implied or otherwise.


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  • Location
    Monrovia, California
  • Department
    Information Technology
  • Employment Type
    Full Time
  • Minimum Experience