Manager/Sr. Manager, Contracts Manager

Legal · San Diego, California
Department Legal
Employment Type Full Time
Minimum Experience Senior Manager/Supervisor

Xencor is an innovative, clinical-stage biopharmaceutical company located in the Los Angeles area—near Pasadena—and in San Diego. We use our pioneering XmAb® technology to discover and develop better biotherapeutics, antibodies and cytokines with improved function, with the goal of improving patient outcomes and quality of life. We have an excellent opportunity for a Manager/Sr. Manager, Contracts Manager-reporting into the Legal department to join our team.


Our protein engineering capabilities and the modular nature of our XmAb technology allow us to quickly identify and create new platforms and drug candidates for potential development. We are advancing a deep clinical pipeline of novel drug candidates, including eight bispecific antibodies and two engineered cytokines, and more programs are expected to start clinical testing in 2022. We also leverage our many XmAb technologies by collaborating with leading global biopharmaceutical companies, including Genentech and Janssen Biotech, among others, and including our partnerships, 20 XmAb drug candidates are advancing through clinical development. Three XmAb medicines, to treat patients with a range of serious illnesses, such as aggressive lymphoma, rare blood disorders and COVID-19, are now marketed worldwide by partners.


Our employees are the most important factor in our success, and we have assembled a highly talented group from diverse backgrounds and disciplines to execute our business plan and shape our future. Xencor employees’ value new ideas and flexibility and demand from each other scientific rigor, a passion for innovation, and a willingness to take risks.


We currently have an excellent opportunity for a talented Manager/Sr. Manager Contracts Manager, reporting into the Legal department to join our team!  


 Responsible for the management, negotiation, and completion of legal vendor and consultant contracts.

Primary Responsibilities:

  • Manages the contract lifecycle by drafting, negotiating, and managing contracts and change orders, including the active negotiation of scope of work, payment terms and budgets from inception to completion
  • Leads, facilitates and assists the contract development, tracking and filing process across the organization   
  • Coordinates the processing of contracts from the identification of need through execution, including analysis to support business goals, negotiating according to playbook and escalating to Legal as necessary
  • Liaises with multiple departments to assist with the negotiation of the scope, terms and budget proposals for contracts with outside vendors and consultants
  • Quantifies and/or reviews contract specifications and determines pricing to reach agreement
  • Works within Xencor systems to obtain financial approval of spend and subsequent gathering of required approvals and signatures
  • Oversees and maintains company contract management system, contract central repository (uploading and QC’ing contracts) and contract expiration reports and renewals
  • Prepares reports and metrics relating to the contract process, as needed
  • Manages high volume of proposal and contract requests to keep process and project timelines.
  • Responds to inquiries from internal groups, sites, vendors, and consultants professionally, efficiently, and effectively, with any necessary follow up
  • Exercises good judgment within a defined departmental contract playbook with minimal supervision
  • Leads and contributes to complex functional or company initiatives and special projects as identified by clinical management or business needsStays up to date with all applicable regulations, industry contracting standards/best practices, and implements all applicable regulations, standards, and changes into practice
  • Adheres to all department and company-wide policies regarding conduct, performance and procedures
  • Performs other duties as assigned.


Position requires a bachelor’s degree and at least 6 years related experience in a clinical trial setting and/or in a role of Contract Analyst/Manager in the pharmaceutical industry.  Requires at least 3 years in contracts management, process flow, including experience working with vendors and internal groups negotiating and executing on different contract types.  Previous experience in a small biotech preferred. 

Position also requires:

  • Strong client focus, dedicated to meeting the expectations and requirements of internal and external customers
  • Knowledge in current and emerging contracting practices; including trends and new technology 
  • Ability to skillfully negotiate through tough situations with both internally and externally  with diplomacy
  • Flexible in communication approach; direct and forceful as well as diplomatic and able to gain trust quickly of other parties
  • Exceptional analytical, organizational and communication skills (verbal, written, presentation)
  • Ability to prioritize and balance time, actions, and projects to ensure accomplishment of results
  • Ability to anticipate and addresses obstacles, redirecting efforts to accelerate the work or improve quality
  • Ability to think critically and creatively in a fast-paced, changing environment
  • Ability to operate with the highest level of integrity and to maintain confidentiality.
  • Understanding the big picture while maintaining strong detail orientation
  • Ability to effectively cope with high-pressure situations; can comfortably refocus and reprioritize as demands change; can comfortably evaluate and make decisions with imperfect or incomplete information; and can analyze a playbook and exercise good judgement in applying principles consistently across different scenarios.

Physical, Mental and Environment Demands:

The physical, mental and working environment demands described are representative of those that must be met by an employee to successfully perform the primary functions of this position.


The physical demands of the office are normally associated with extended amounts of time sitting and using office equipment, including a computer, keyboard and mouse, which can cause muscle strain. While performing the duties of this job, the employee is frequently required to stand, walk and sit. Periodic light lifting of supplies and materials may apply.


Specific mental demands for the position are listed above under requirements.  In addition, mental demands for this position include:

  • Ability to multitask without loss of efficiency or accuracy, including the ability to perform multiple duties from multiple sources.
  • Ability to work and sustain attention with distractions and/or interruptions.
  • Ability to interact appropriately with a variety of individuals including vendors, customers and clients.
  • Ability to maintain regular attendance and be punctual.
  • Ability to understand, remember and follow verbal and written instructions.

Occasional travel may be required, including travel between Xencor’s Monrovia and San Diego offices. Work for this position is generally performed at Xencor’s worksite and requires full-time commitment.

Xencor requires all employees to be fully vaccinated against COVID-19 as a condition of employment.  Being fully vaccinated means that at least two weeks have passed since an individual’s final dose of an authorized COVID-19 vaccine regimen, including any boosters recommended by the CDC.  New employees will be required to provide proof of their fully COVID-19 vaccinated status as of their start date unless an exemption or accommodation is approved. 


Americans with Disabilities Act (ADA) Statement

The Company will provide reasonable accommodations (such as a qualified sign language interpreter or other personal assistance) with the application process upon your request as required to comply with applicable laws. If you have a disability and require assistance in this application process, please contact


To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. Reasonable Accommodations may be made to enable qualified individuals with disabilities to perform the essential functions.


Equal Employment Opportunity (EEO) Statement

The Company is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender or gender identity, national origin, disability status, protected veteran status or any other characteristic protected by state or federal law.


Xencor does not accept profiles or resumes from recruiting vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by Xencor, implied or otherwise.


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  • Location
    San Diego, California
  • Department
  • Employment Type
    Full Time
  • Minimum Experience
    Senior Manager/Supervisor