Sr. Manager/AD Project Planner, Oncology Programs

Project Leadership & Alliance Management · San Diego, California
Department Project Leadership & Alliance Management
Employment Type Full Time
Minimum Experience Experienced

Xencor is an innovative, clinical-stage biotechnology company located in the Los Angeles area (near Pasadena) and in San Diego. We use our pioneering XmAb® technology to discover and develop better biotherapeutics – antibodies and other proteins with improved function – with the goal of improving patient outcomes and quality of life, and we have an excellent opportunity for a Sr. Manager/Associate Director, Project Planner to join our team.


Our protein engineering capabilities and the modular nature of our technology allow us to quickly identify and create new platforms and drug candidates for potential development. We are developing a broad portfolio enabled by the rapid expansion of our bispecific technologies, and nine XmAb bispecific antibodies and cytokines are in clinical testing. We also leverage our many XmAb technologies by engaging in multiple collaborations with leading global biopharmaceutical companies, including Novartis, Amgen and Genentech, among others. Including our partners, over a dozen XmAb drug candidates are advancing through clinical development, and the first antibody that incorporates an XmAb technology has been approved for commercial marketing worldwide.


Our employees are the most important factor in our success and we have assembled a highly talented group from diverse backgrounds and disciplines to execute our business plan and shape our future. Xencor employees value new ideas and flexibility and demand from each other scientific rigor, a passion for innovation, and a willingness to take risks.


We seek a Sr. Manager/Associate Director, Project Planner, with at least 3 years of experience in project planning/project management and applicable pharmaceutical industry experience. The incumbent will be responsible for the generation, management, and maintenance of high-quality project schedules associated with pipeline programs in research and in clinical development. The Manager, Project Planner possesses a comprehensive knowledge/understanding of drug development, resource management concepts, associated business processes, and project planning software. The Manager, Project Planner typically works within a cross-functional team environment, contributes or may lead/co-lead moderately complex sub-team initiatives, and plays an essential role in supporting the management of evolving priorities within the portfolio. 


Job Duties and Responsibilities:

  • Responsible for coordinating, monitoring and reporting project schedule and resource management information to enable alignment of functional schedules and FTE/dollar resources into the project macro view.
  • Supports delivery of pre-IND programs by constructing scoped investment modules for emerging programs then supporting their management as priorities evolve
  • Produces what-if scenario analyses (base, optimistic and pessimistic development) based on context obtained from project team members
  • Monitors progress of project activities towards next project milestone, anticipates and highlights potential variances, supports line/team in critical path analyses and understanding the impact, and partners with the program PM, Clinical Operations, and the project team to support issue mitigation.
  • Performs scenario planning of project timelines within and across protocols and across therapeutic area/portfolio to enable optimum use of local, global, and outsourced resources to ensure efficient delivery of project milestones.
  • Provides appropriate support to enable effective portfolio management activities.
  • Utilizes available reporting and visualization tools to support governance and team reporting needs 
  • Contributes to continuous improvement of reporting tools, project plans, plan generation, plan utilization, and/or report creation/development processes.
  • Contributes to risk management through the identification of operational and project/program risks for discussion with appropriate team leadership. Participates in team discussions to de-risk projects and develop new options to resolve moderately complex issues.
  • Depending on level of experience/career interests, may be asked to support team documents (e.g., minutes) and other PM activities
  • Willingness to travel between Monrovia and San Diego if needed


Job Qualifications and Requirements: 

  • At least 3 years experience in project planning and/or project management in the pharmaceutical/biotech industry.
  • Pre-IND to Phase 1/2 experience required
  • Preferred areas of knowledge include oncology or autoimmune disease expertise, monoclonal antibody development expertise, global IND/BLA requirements.
  • Experienced with planning tools (e.g., Smartsheet, MS Project, SharePoint) and office software (e.g., MS Office, Business Objects, Spotfire).
  • Ability to partner/negotiate with cross-functional teammates from research, pre-clinical development, manufacturing, quality, regulatory, clinical operations and clinical development.
  • Detail oriented, but also values that details serve the higher-level strategy
  • Proficiency with competitive market research tools a plus



Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.


Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.


Physical Demands:
The physical demands described are representative of those that must be met by an employee to successfully perform the primary functions of this position.


The physical demands of the office are normally association with extended amounts of time sitting and using office equipment, including a computer, keyboard and mouse, which can cause muscle strain. While performing the duties of this job, the employee is frequently required to stand, walk and sit. Periodic light lifting of supplies and materials may apply. Work is performed in an office environment.

Americans with Disabilities Act (ADA) Statement

The Company will provide reasonable accommodations (such as a qualified sign language interpreter or other personal assistance) with the application process upon your request as required to comply with applicable laws. If you have a disability and require assistance in this application process, please contact

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. Reasonable Accommodations may be made to enable qualified individuals with disabilities to perform the essential functions.

Equal Employment Opportunity (EEO) Statement

The Company is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender or gender identity, national origin, disability status, protected veteran status or any other characteristic protected by state or federal law.

Xencor does not accept profiles or resumes from recruiting vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by Xencor, implied or otherwise.

Thank You

Your application was submitted successfully.

  • Location
    San Diego, California
  • Department
    Project Leadership & Alliance Management
  • Employment Type
    Full Time
  • Minimum Experience