CON- Research Associate

Bio-Analytical Development · Monrovia, California
Department Bio-Analytical Development
Employment Type Contractor
Minimum Experience Experienced

Xencor is an innovative, clinical-stage biopharmaceutical company located in the Los Angeles area (near Pasadena) and in San Diego. We use our pioneering XmAb® technology to discover and develop better biotherapeutics – antibodies and other proteins with improved function – with the goal of improving patient outcomes and quality of life, and we have an excellent opportunity for a Research Associate to join our team.

 

Our capabilities and the modular nature of XmAb technology allows us to quickly identify and create new platforms and drug candidates for potential development. We are developing a deep pipeline of novel drug candidates enabled by the rapid expansion of our bispecific antibody and cytokine technologies. Nine XmAb bispecific antibody programs are in clinical testing, and more are expected to start clinical testing in 2021. We also leverage our many XmAb technologies by engaging in multiple collaborations with leading global biopharmaceutical companies, including Novartis, Amgen and Genentech, among others. We and our partners are advancing 18 XmAb drug candidates through clinical development, and two medicines that incorporate XmAb technology are approved for commercial marketing.

 

Job Duties include:

  • Perform functional cell based assays to deliver potency and NAb data and
  • Perform immunoassays to deliver PK, ADA and biomarker data in support of research and GxP studies
  • Develop assays for large molecule drug development
  • Analyze (use of WinNonLin, SoftMax, GraphPad etc.) and report data as per established timelines
  • Maintain mammalian cell cultures; generate master and working cell banks
  • Maintain reagent inventory and laboratory equipment
  • Follow developing and established standard operating procedures in a regulated laboratory (GMP)
  • Maintain compliant records

 

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

 

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

 

Qualifications:

  • Bachelor’s degree in biological sciences with 10+ years Industry experience or Master’s degree in Biological sciences with 5+ years Industry experience.
  • Experience in design, development, and execution of assays for large molecule drug development
  • Experience in Immunoassays (e.g. ELISA, MSD, TRF) and/or Bioassays (e.g. neutralizing antibody, phosphorylation, caspase, cytotoxicity, ADCC, reporter expression, cell proliferation) in a regulated medical/research lab desired.
  • Proficient in common software and data analysis packages (eg, SoftMax Pro, GraphPad Prism, JMP; Microsoft Office: PowerPoint, Excel, Word, Outlook)
  • PK Analysis with WinNonLin is a plus
  • Detail oriented, good documentation practice and strong organizational skills
  • General lab experience including operating basic laboratory equipment such as pipettes (precision pipetting), centrifuge, and microscope.
  • Strong interpersonal skills and ability to work well in a team
  • Excellent verbal and written communication skills

 

We strive to create an environment that will challenge, motivate, and reward our employees for meeting the changing demands of creating breakthrough therapeutics. Xencor has a highly collaborative structure that integrates co-workers with different skill sets into teams for product and technology development.  With an emphasis on attaining the best and most highly qualified candidates in their respective fields, we offer a competitive salary & benefits package. Please submit a cover letter & resume.  For further information about Xencor, please visit our website atwww.xencor.com   EOE

 

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  • Location
    Monrovia, California
  • Department
    Bio-Analytical Development
  • Employment Type
    Contractor
  • Minimum Experience
    Experienced