Associate Director/Director, Toxicology
Monrovia or San Diego
Xencor is an innovative, clinical-stage biotechnology company located in the Los Angeles area (near Pasadena) and in San Diego. We use our pioneering XmAb® technology to discover and develop better biotherapeutics – antibodies and other proteins with improved function – with the goal of improving patient outcomes and quality of life, and we have an excellent opportunity for a/an [insert title] to join our team.
Our protein engineering capabilities and the modular nature of our technology allow us to quickly identify and create new platforms and drug candidates for potential development. We are developing a broad portfolio enabled by the rapid expansion of our bispecific technologies, and nine XmAb bispecific antibodies and cytokines are in clinical testing. We also leverage our many XmAb technologies by engaging in multiple collaborations with leading global biopharmaceutical companies, including Novartis, Amgen and Genentech, among others. Including our partners, over a dozen XmAb drug candidates are advancing through clinical development, and the first antibody that incorporates an XmAb technology has been approved for commercial marketing worldwide.
We seek a Toxicologist to lead the nonclinical safety evaluation and strategic development of engineered antibody therapeutic products. The role includes the design, execution, analysis, and reporting of mostly non-human primate studies (non-GLP and GLP) performed exclusively at contract laboratories. In addition, the successful candidate will represent Preclinical Sciences on research program and clinical development teams and lead the teams through assembly of scientifically-sound, nonclinical regulatory packages and query responses. The role is not responsible for the conduct of research pharmacology or animal models of disease studies, though understanding them in consideration of toxicology study results is important.
Responsibilities include but are not limited to*:
*Please note this job description is not written to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.
**Xencor does not accept profiles or resumes from recruiting vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by Xencor, implied or otherwise.
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