Xencor is an innovative, clinical-stage biotechnology company located in the Los Angeles area (near Pasadena) and in San Diego. We use our pioneering XmAb® technology to discover and develop better biotherapeutics – antibodies and other proteins with improved function – with the goal of improving patient outcomes and quality of life, and we have an excellent opportunity for a Lead Scientist, Preclinical PK/PD/Toxicology.
Our capabilities and the modular nature of our technology allow us to quickly identify and create new platforms and drug candidates for potential development. We are developing a deep pipeline of novel drug candidates enabled by the rapid expansion of our bispecific technologies, and seven XmAb bispecific antibody programs are in clinical testing. We also leverage our many XmAb technologies by engaging in multiple collaborations with leading global biopharmaceutical companies, including Novartis, Amgen and Genentech, among others. Including our partners, over a dozen XmAb drug candidates are advancing through clinical development, and the first antibody that incorporates an XmAb technology has been approved for commercial marketing in the United States.
Our employees are the most important factor in our success and we have assembled a highly talented group from diverse backgrounds and disciplines to execute our business plan and shape our future. Xencor employees value new ideas and flexibility and demand from each other scientific rigor, a passion for innovation, and a willingness to take risks.
We are seeking an in vivo Pharmacokinetics, Pharmacodynamics, Toxicology (PK/PD/Tox) scientist to design and execute Preclinical drug development studies evaluating and informing lead clinical candidate selection for engineered antibody therapeutics focused primarily, but not exclusively, on immuno-oncology. This is a Project Team Representative role that liaises with Xencor discovery and development project teams to design, analyze, and interpret in vivo studies performed at contract laboratories. The role does not include research pharmacology or animal models of disease. Grade level to be commensurate with experience and internal calibration.
This position reports to the Senior Director, Preclinical.
Some responsibilities include:
Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
*Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.
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